#Molecular diagnostics examples full
#Molecular diagnostics examples iso

PCR is now the most commonly used molecular diagnostic tool, offering a very sensitive and rapid approach for the detection, identification, and quantification of specific DNA or RNA targets. Data from the Human Genome Project have opened up many possible targets for detection, prevention and/or treatment of disease. Both scientific milestones have served to expand the usefulness and range of applicability for molecular diagnostic approaches. The revolution in molecular diagnostics came with the adoption of the polymerase chain reaction (PCR) and the completion of the Human Genome Project. Molecular diagnostics covers a range of techniques from fluorescent in-situ hybridization (FISH), DNA-chip technology, mass spectrometry, as well as nucleic acid amplification tests (NAATs). While clinical genetics has become almost entirely molecular-based, traditional morphological analysis, chemical analysis, and immunohistochemistry will always have a place in many areas. Although molecular biology has been a field of study for over 50 years, the integration of molecular diagnostics into pathological fields has been variable. Diagnostic tests must demonstrate clinical utility, while at the same time adhere to strict quality requirements for reproducibility, along with appropriate sensitivity and specificity performance. Technology common within a research environment is not always readily adopted in a diagnostic setting. Results from molecular diagnostic tests are used in conjunction with the presented symptoms and clinical expertize of the serving physician to better understand disease aetiology, pathogenesis, diagnosis and prognosis.

#Molecular diagnostics examples full

Molecular-based tests can cover a range of clinical conditions from inherited genetic disease, through the full range of cancers, infectious disease agents, drug-dose or treatment response scenarios (pharmacogenomics), and even personalized treatment and prognostic investigations based upon individual genetic make-up (personalized medicine). Molecular diagnostic approaches utilize nucleic acid detection techniques to analyse target DNA or RNA from an affected individual. What is Molecular Diagnostics?ĭiagnostic or clinical pathology plays an essential role in patient care – providing physicians with the specific information required to identify and treat the very broad range of ailments presented across primary doctor or hospital practice settings. In addition, our custom assay development services can provide the edge required for optimal performance and expedient development of your next molecular diagnostic assay.

#Molecular diagnostics examples iso

With ISO 13485 manufacturing standards, each reagent represents the level of quality required when developing tests for the clinical market. Meridian offers a range of products and services to support the research that contributes towards development of diagnostic products and testing services. There is very real potential for molecular diagnostics to revolutionize patient care, offering tools that go further than simple characterization of disease, reaching into the domain of characterizing the patient.

The field of molecular diagnostics has seen much growth in the clinical setting, providing rapid and sensitive approaches for the detection and monitoring of a wide range of human ailments.